Go - Southern Illinois Eclipse

Quality Inn

13201 Kessler Rd
Cairo, IL 62914
(618) 734-0215
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Stay near the banks of the Ohio and Mississippi rivers at the Quality Inn� hotel in Cairo, Illinois. Our location off Interstate 57 provides convenient access to:

  • Fort Defiance State Park

  • Wickliffe Mounds State Park

  • Magnolia Manor

  • Cypress Creek National Wildlife Refuge


Our proximity to the neighboring states of Missouri and Kentucky provide even more to see and do. Explore Cairo�s historic district, where you�ll find the Old Custom House, a former post office and courthouse that now serves as a museum. Several shops and restaurants are also close by.